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White Papers

Bridging the gap …

How to develop effective in vitro assays for early drug discovery

Integrating process and discovery chemistry to design out problems at an earlier stage

Posters & Presentations

Rapid Optimization of a Buchwald–Hartwig Amination using DoE

Bioisosteres

Computer-aided Drug Design at Charnwood Discovery

Photochemistry – Cross-Coupling via Metallaphotorededox

IKA ElectraSyn 2.0 Pro – Electrochemical Nickel-Catalyzed Aryl-Halide Amination

Using SPR to Drive Integrated Screening Projects

Using SPR to Characterize the Binding Modes of PROTAC Molecules

Structure-based Virtual Screening to Identify Novel BRD4 Inhibitors

Beyond Degradation: Cell-based and Biophysical PROTAC Characterization

Protein Detection Capabilities

Investigating 3D Tumour Spheroids and Immune Cell Models

PD-1/PD-L1 Inhibitors

Webinars

Beyond Degradation: Cell-based and Biophysical PROTAC Characterization using BRD4 as a Target

QM-SAR: Quantum Mechanics Structure-Activity Relationship Webinar

Technical Papers

Case Studies

medicinal chemistry case study

Medicinal Chemistry and Preclinical PR&D from Discovery Lead to Development Candidate 1

Chemical Development, Discovery Chemistry

Charnwood Discovery

Medicinal Chemistry Lead Optimisation (LO) 1

Discovery Chemistry

medicinal chemistry case study

Medicinal Chemistry Hit-to-Lead (H2L) 2

Discovery Chemistry

medicinal chemistry case study

Medicinal Chemistry: Hit-to-Lead (H2L)

Discovery Chemistry

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