Posters & Presentations

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Posters & Presentations

Rapid Optimization of a Buchwald–Hartwig Amination using DoE

Bioisosteres

Computer-aided Drug Design at Charnwood Discovery

Photochemistry – Cross-Coupling via Metallaphotorededox

IKA ElectraSyn 2.0 Pro – Electrochemical Nickel-Catalyzed Aryl-Halide Amination

Using SPR to Drive Integrated Screening Projects

Using SPR to Characterize the Binding Modes of PROTAC Molecules

Structure-based Virtual Screening to Identify Novel BRD4 Inhibitors

Beyond Degradation: Cell-based and Biophysical PROTAC Characterization

Protein Detection Capabilities

Investigating 3D Tumour Spheroids and Immune Cell Models

PD-1/PD-L1 Inhibitors

Grow Your Own Brain Cells

Senescence, the Secret to Living Forever?

Pre-clinical Discovery Using Simple Western for Protein Detection

Molecular Glues – Developing a Robust Screening Cascade

Rapid Optimization and Synthesis of New Phenanthroline Amino Acid Ligands using DoE

Use of the Thermo Scientific™ Vanquish Horizon UHPLC and Orbitrap Exploris™ 120 in Discovery DMPK

Phenotypic Assays – Diving into the Cellular Response to Expand the “Druggable” Target Space

Speeding up PROTAC Development: A Direct-to-Biology Approach

A Direct-to-Biology Approach for Rapid Synthesis and Profiling of PROTACs

Case Studies

oncology banner

Developing Whole Cell NanoBRET Target Engagement Assays for Three Homologous ATPases

photochem_Banner

Application of Photoredox Catalysis for Late-stage Functionalization

Discovery Chemistry

Autophagy assay development

TRESK: Sensory Physiology and Pain Identification of Channel Activators and Inhibitors

Streamling the thoughput of western blotting

Biomarkers

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