Photochemistry – Cross-Coupling via Metallaphotorededox

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At Charnwood Discovery, we investigated the application of photocatalytically-generated silyl radical species in cross-coupling reactions, as reported by MacMillan and co-workers in 2016.

Access to metallophotocatalysis has given Charnwood Discovery the capability to synthesis a diverse set of compounds. The versatility of functional groups permitted by this technique and accessibility of in-house blue LED reactor, means that we will now have access to a new range of reactions and products for drug discovery.

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