Charnwood Discovery worked closely with a US Biotech company, providing route optimization for a lead candidate. Learn more here:
- US Biotech company (Oncology target)
- Supported by up to 6 FTEs for 18 months
- Elaboration of existing hits to elucidate SAR
- Rational design to deliver drug-like compounds
- Compounds screened by client (biochemical assays)
- >80 compounds prepared over numerous series
- Highly potent compounds with good ADME properties, clear SAR and in vivo efficacy
- Route scouting and route optimization for a lead candidate and technical transfer to a North American GMP manufacturer
Our goal is to enable the supply of novel preclinical candidates. Never underestimate the challenges of moving from discovery, through optimisation into the development of a scalable route for large-scale synthesis.
With Charnwood Discovery you can be confident that our in-house discovery and development teams share the culture and ethos of our company: excellence in everything we do, nurtured by close collaboration and communication.
