Discover how the latest advances in high-resolution mass spectrometry (HRMS) are transforming discovery Drug Metabolism and Pharmacokinetics (discovery DMPK). This poster highlights the shift from traditional triple quadrupole systems to cutting-edge HRMS instruments, like the Thermo Scientific™ Orbitrap Exploris™ 120, for more informative data acquisition.
Find out how we:
- Achieve reliable sensitivity and excellent dynamic range in full scan analysis with high resolution and accurate mass capability.
- Save significant time by eliminating the need for MS/MS method development.
- Handle challenging compounds, including PROTACs and peptides, with ease.
- Identify metabolites and potential issues in a single analysis.
Learn how the Orbitrap Exploris™ 120, paired with the Thermo Scientific™ Vanquish UHPLC system, delivers robust, sensitive, and reproducible data for both in vitro and in vivo discovery DMPK assays.



