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The ADME / DMPK team will be heading out to industry events in September and presenting our latest poster. It outlines how the application of cutting-edge HRMS instruments, like the Thermo Scientific™ Orbitrap Exploris™ 120, can achieve more informative data acquisition. See colleagues at the following events:

DMDG's 50th Open Meeting 2024

The DMDG Autumn Meeting 2024, taking place from 2-4 September in York, focuses on advancements in drug metabolism and pharmacokinetics (DMPK). The event will feature a robust program of expert presentations, workshops, and networking opportunities designed for professionals in the pharmaceutical sciences. Attendees will gain insights into the latest research, innovative techniques, and regulatory considerations shaping the field. The meeting offers a platform for scientific exchange, fostering collaborations that drive progress in drug development and therapeutic innovation.

For more information, visit the DMDG website.

BMSS-BSPR Super Meeting 2024

The BMSS-BSPR Super Meeting 2024, scheduled for 4-6 September in Warwick, is a premier event for mass spectrometry and proteomics professionals. It will bring together leading scientists and industry experts to discuss the latest developments in these fields. The meeting features a comprehensive program, including keynote lectures, workshops, and networking opportunities, aimed at fostering collaboration and innovation in mass spectrometry and proteomics.

For more details, visit the BMSS website.

About the Poster

Discover how the latest advances in high-resolution mass spectrometry (HRMS) are transforming discovery Drug Metabolism and Pharmacokinetics (discovery DMPK). This poster highlights the shift from traditional triple quadrupole systems to cutting-edge HRMS instruments, like the Thermo Scientific™ Orbitrap Exploris™ 120, for more informative data acquisition.

Find out how we:

  • Achieve reliable sensitivity and excellent dynamic range in full scan analysis with high resolution and accurate mass capability.
  • Save significant time by eliminating the need for MS/MS method development.
  • Handle challenging compounds, including PROTACs and peptides, with ease.
  • Identify metabolites and potential issues in a single analysis.

Learn how the Orbitrap Exploris™ 120, paired with the Thermo Scientific™ Vanquish UHPLC system, delivers robust, sensitive, and reproducible data for both in vitro and in vivo discovery DMPK assays.

In addition to in vitro ADME assays, Charnwood Discovery offers the following services to support clients in identifying the best drug candidates and advancing their projects.

Our core capabilities, in addition to ADME / DMPK services, are

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